Cholesterol biosynthesis pathway as a novel mechanism of resistance to estrogen deprivation in estrogen receptor-positive breast cancer
2016 · Breast Cancer Research · 134 citations
https://doi.org/10.1186/s13058-016-0713-5
S
Sunil Pancholi
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Sunil Pancholi is an academic researcher from Institute of Cancer Research. The author has contributed to research in topics: Estrogen and related hormone effects & Advanced Breast Cancer Therapies & HER2/EGFR in Cancer Research. The author has an h-index of 25, co-authored 152 publications.
ORCID: 0000-0002-0880-1588Papers by this author
worksThe Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer
2019 · Cell Reports · 91 citations
https://doi.org/10.1016/j.celrep.2019.09.032
Lapatinib Restores Hormone Sensitivity with Differential Effects on Estrogen Receptor Signaling in Cell Models of Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer with Acquired Endocrine Resistance
2010 · Clinical Cancer Research · 87 citations
https://doi.org/10.1158/1078-0432.ccr-09-1764
ERBB2 influences the subcellular localization of the estrogen receptor in tamoxifen-resistant MCF-7 cells leading to the activation of AKT and RPS6KA2
2008 · Endocrine Related Cancer · 81 citations
https://doi.org/10.1677/erc-07-0240
Preclinical and clinical studies of estrogen deprivation support the PDGF/Abl pathway as a novel therapeutic target for overcoming endocrine resistance in breast cancer
2012 · Breast Cancer Research · 43 citations
https://doi.org/10.1186/bcr3191
Effectiveness and molecular interactions of the clinically active mTORC1 inhibitor everolimus in combination with tamoxifen or letrozole in vitro and in vivo
2012 · Breast Cancer Research · 33 citations
https://doi.org/10.1186/bcr3330
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