Allosteric Inhibition of SHP2: Identification of a Potent, Selective, and Orally Efficacious Phosphatase Inhibitor
2016 · Journal of Medicinal Chemistry · 284 citations
https://doi.org/10.1021/acs.jmedchem.6b00680
M
Michelle Fodor
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Michelle Fodor is an academic researcher from Novartis (United States). The author has contributed to research in topics: Protein Tyrosine Phosphatases & Galectins and Cancer Biology & Bioactive Compounds and Antitumor Agents. The author has an h-index of 13, co-authored 28 publications.
Papers by this author
worksStructural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition
2018 · Nature Communications · 163 citations
https://doi.org/10.1038/s41467-018-06823-9
Structure of the MRAS–SHOC2–PP1C phosphatase complex
2022 · Nature · 48 citations
https://doi.org/10.1038/s41586-022-05086-1
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