The small molecule GAT1508 activates brain-specific GIRK1/2 channel heteromers and facilitates conditioned fear extinction in rodents
2020 · Journal of Biological Chemistry · 28 citations
https://doi.org/10.1074/jbc.ra119.011527
T
Takeharu Kawano
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Takeharu Kawano is an academic researcher from Northeastern University. The author has contributed to research in topics: Ion channel regulation and function & Receptor Mechanisms and Signaling & Cardiac electrophysiology and arrhythmias. The author has an h-index of 18, co-authored 48 publications.
Papers by this author
worksUnifying Mechanism of Controlling Kir3 Channel Activity by G Proteins and Phosphoinositides
2015 · International review of neurobiology · 25 citations
https://doi.org/10.1016/bs.irn.2015.05.013
A novel small-molecule selective activator of homomeric GIRK4 channels
2022 · Journal of Biological Chemistry · 21 citations
https://doi.org/10.1016/j.jbc.2022.102009
Hydrogen sulfide inhibits Kir2 and Kir3 channels by decreasing sensitivity to the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2)
2018 · Journal of Biological Chemistry · 19 citations
https://doi.org/10.1074/jbc.ra117.001679
Hypoxia inhibits the cardiac I current through SUMO targeting Kir2.1 activation by PIP2
2022 · iScience · 7 citations
https://doi.org/10.1016/j.isci.2022.104969
Optogenetic dephosphorylation of phosphatidylinositol 4,5 bisphosphate in Xenopus laevis oocytes
2023 · STAR Protocols · 7 citations
https://doi.org/10.1016/j.xpro.2022.102003
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