Docking pose of etoposide in Top2α and development of complex-based pharmacophore.
2015 · Figshare · 0 citations
https://doi.org/10.1371/journal.pone.0114904.g001
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P. G. Wakelin Laurence
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P. G. Wakelin Laurence is an academic researcher. The author has contributed to research in topics: Synthesis and biological activity & Cancer therapeutics and mechanisms & Peptidase Inhibition and Analysis.
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worksCompounds suggested from Top2α docking studies.
2015 · Figshare · 0 citations
https://doi.org/10.1371/journal.pone.0114904.t001
Possible residues to be targeted by Top2α versus Top2β-selective molecules.
2015 · Figshare · 0 citations
https://doi.org/10.1371/journal.pone.0114904.g003
Top2α and β cleavage assays with selected compounds.
2015 · Figshare · 0 citations
https://doi.org/10.1371/journal.pone.0114904.g005
Compounds selected from screening with etoposide pharmacophores – biological results.
2015 · Figshare · 0 citations
https://doi.org/10.1371/journal.pone.0114904.t002
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