The Chemistry Development Kit (CDK) v2.0: atom typing, depiction, molecular formulas, and substructure searching
2017 · Journal of Cheminformatics · 566 citations
https://doi.org/10.1186/s13321-017-0220-4
R
Rajarshi Guha
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Rajarshi Guha is an academic researcher from Vertex Pharmaceuticals (United States). The author has contributed to research in topics: Computational Drug Discovery Methods & Ovarian cancer diagnosis and treatment & Microtubule and mitosis dynamics. The author has an h-index of 57, co-authored 323 publications.
ORCID: 0000-0001-7403-8819Papers by this author
worksOpen Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond
2016 · PLoS Pathogens · 445 citations
https://doi.org/10.1371/journal.ppat.1005763
RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription
2016 · Cell · 293 citations
https://doi.org/10.1016/j.cell.2016.02.036
Modelling of compound combination effects and applications to efficacy and toxicity: state-of-the-art, challenges and perspectives
2015 · Drug Discovery Today · 202 citations
https://doi.org/10.1016/j.drudis.2015.09.003
ATR Inhibitors VE-821 and VX-970 Sensitize Cancer Cells to Topoisomerase I Inhibitors by Disabling DNA Replication Initiation and Fork Elongation Responses
2014 · Cancer Research · 164 citations
https://doi.org/10.1158/0008-5472.can-13-3369
Chemical Genomic Profiling for Antimalarial Therapies, Response Signatures, and Molecular Targets
2011 · Science · 140 citations
https://doi.org/10.1126/science.1205216
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