Consecutive radical <i>S</i> -adenosylmethionine methylations form the ethyl side chain in thienamycin biosynthesis
2015 · Proceedings of the National Academy of Sciences · 89 citations
https://doi.org/10.1073/pnas.1508615112
C
Craig A. Townsend
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Craig A. Townsend is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Microbial Natural Products and Biosynthesis & Mycotoxins in Agriculture and Food & Chemical Synthesis and Analysis. The author has an h-index of 61, co-authored 293 publications.
ORCID: 0000-0003-2795-7585Papers by this author
worksStructure of a B12-dependent radical SAM enzyme in carbapenem biosynthesis
2022 · Nature · 63 citations
https://doi.org/10.1038/s41586-021-04392-4
Chromobacterium spp. mediate their anti-Plasmodium activity through secretion of the histone deacetylase inhibitor romidepsin
2018 · Scientific Reports · 54 citations
https://doi.org/10.1038/s41598-018-24296-0
Dissection of the Stepwise Mechanism to β-Lactam Formation and Elucidation of a Rate-determining Conformational Change in β-Lactam Synthetase
2008 · Journal of Biological Chemistry · 29 citations
https://doi.org/10.1074/jbc.m805390200
Improved asymetric synthesis of (-)-3-aminonocardicinic acid and further observations of the mitsunobu reaction for β-lactam formation in seryl peptides
1982 · Tetrahedron Letters · 20 citations
https://doi.org/10.1016/s0040-4039(00)85732-9
Development of a penem antibiotic against Mycobacteroides abscessus
2020 · Communications Biology · 19 citations
https://doi.org/10.1038/s42003-020-01475-2
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