ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways
2017 · Nature Communications · 70 citations
https://doi.org/10.1038/s41467-017-00221-3
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Evan R. Abt
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Evan R. Abt is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: interferon and immune responses & Cytokine Signaling Pathways and Interactions & Cancer Mechanisms and Therapy. The author has an h-index of 13, co-authored 83 publications.
ORCID: 0000-0002-3160-7134Papers by this author
worksPurine nucleoside phosphorylase enables dual metabolic checkpoints that prevent T cell immunodeficiency and TLR7-associated autoimmunity
2022 · Journal of Clinical Investigation · 37 citations
https://doi.org/10.1172/jci160852
Reprogramming of nucleotide metabolism by interferon confers dependence on the replication stress response pathway in pancreatic cancer cells
2022 · Cell Reports · 29 citations
https://doi.org/10.1016/j.celrep.2021.110236
PGC-1α drives small cell neuroendocrine cancer progression toward an ASCL1-expressing subtype with increased mitochondrial capacity
2024 · Proceedings of the National Academy of Sciences · 11 citations
https://doi.org/10.1073/pnas.2416882121
Supplementary Fig. 2 from MEK inhibition sensitizes pancreatic cancer to STING agonism by tumor-cell intrinsic amplification of type I interferon signaling
2024 · 0 citations
https://doi.org/10.1158/1078-0432.27031741
Supplementary Data 1 from MEK inhibition sensitizes pancreatic cancer to STING agonism by tumor-cell intrinsic amplification of type I interferon signaling
2024 · 0 citations
https://doi.org/10.1158/1078-0432.27031747
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