VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington’s disease
2016 · Nature Communications · 193 citations
https://doi.org/10.1038/ncomms12646
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Yu Luo is an academic researcher from Cincinnati Children's Hospital Medical Center. The author has contributed to research in topics: Neurogenesis and neuroplasticity mechanisms & Neuroinflammation and Neurodegeneration Mechanisms & Nuclear Receptors and Signaling. The author has an h-index of 39, co-authored 109 publications.
ORCID: 0000-0002-7939-5505Papers by this author
worksHuman wild-type full-length tau accumulation disrupts mitochondrial dynamics and the functions via increasing mitofusins
2016 · Scientific Reports · 151 citations
https://doi.org/10.1038/srep24756
Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity
2019 · Acta Neuropathologica · 89 citations
https://doi.org/10.1007/s00401-019-01993-2
Inhibition of autophagy blocks cathepsins–tBid–mitochondrial apoptotic signaling pathway via stabilization of lysosomal membrane in ischemic astrocytes
2017 · Cell Death and Disease · 87 citations
https://doi.org/10.1038/cddis.2017.34
Adult microglial TGFβ1 is required for microglia homeostasis via an autocrine mechanism to maintain cognitive function in mice
2024 · Nature Communications · 51 citations
https://doi.org/10.1038/s41467-024-49596-0
Dopaminergic neuron‐specific deletion of p53 gene is neuroprotective in an experimental Parkinson's disease model
2016 · Journal of Neurochemistry · 49 citations
https://doi.org/10.1111/jnc.13706
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