Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance
2018 · Nature Communications · 435 citations
https://doi.org/10.1038/s41467-018-03917-2
D
Dragomir B. Krastev
Claim or correct this author profile
Claim this profile or suggest corrections to the name, affiliation, bio, photo, or paper titles. Approved changes appear as verified CitedEvidence overlays.
103
Papers
3.0K
Citations
18
h-index
23
i10-index
Dragomir B. Krastev is an academic researcher from Institute of Cancer Research. The author has contributed to research in topics: PARP inhibition in cancer therapy & DNA Repair Mechanisms & CRISPR and Genetic Engineering. The author has an h-index of 18, co-authored 88 publications.
ORCID: 0000-0003-4298-7272Papers by this author
worksThe ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin
2022 · Nature Cell Biology · 158 citations
https://doi.org/10.1038/s41556-021-00807-6
PPP2R1A mutations cause ATR inhibitor sensitivity in ovarian clear cell carcinoma
2025 · Oncogene · 9 citations
https://doi.org/10.1038/s41388-024-03265-0
MND1 and PSMC3IP control PARP inhibitor sensitivity in mitotic cells
2023 · Cell Reports · 5 citations
https://doi.org/10.1016/j.celrep.2023.112484
Autocrine interferon poisoning mediates ADAR1-dependent synthetic lethality in BRCA1/2-mutant cancers
2025 · Nature Communications · 1 citations
https://doi.org/10.1038/s41467-025-62309-5
Research topics
topicsChat about Author
Papers
Chat
Click to start Chat