The NLRP3 Inflammasome: An Overview of Mechanisms of Activation and Regulation
2019 · International Journal of Molecular Sciences · 3,259 citations
https://doi.org/10.3390/ijms20133328
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Yuan He
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Yuan He is an academic researcher from Wayne State University. The author has contributed to research in topics: Inflammasome and immune disorders & Heme Oxygenase-1 and Carbon Monoxide & interferon and immune responses. The author has an h-index of 25, co-authored 68 publications.
ORCID: 0000-0003-0779-2613Papers by this author
worksMechanism and Regulation of NLRP3 Inflammasome Activation
2016 · Trends in Biochemical Sciences · 2,619 citations
https://doi.org/10.1016/j.tibs.2016.09.002
Inhibition of <i>METTL3</i> attenuates renal injury and inflammation by alleviating <i>TAB3</i> m6A modifications via IGF2BP2-dependent mechanisms
2022 · Science Translational Medicine · 284 citations
https://doi.org/10.1126/scitranslmed.abk2709
CRISPR/Cas9-Mediated CCR5 Ablation in Human Hematopoietic Stem/Progenitor Cells Confers HIV-1 Resistance In Vivo
2017 · Molecular Therapy · 240 citations
https://doi.org/10.1016/j.ymthe.2017.04.027
Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype
2020 · Cell Death and Disease · 178 citations
https://doi.org/10.1038/s41419-020-2565-2
The leucine-rich repeat (LRR) domain of NLRP3 is required for NLRP3 inflammasome activation in macrophages
2022 · Journal of Biological Chemistry · 27 citations
https://doi.org/10.1016/j.jbc.2022.102717
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