Loss of BRCA1 or BRCA2 markedly increases the rate of base substitution mutagenesis and has distinct effects on genomic deletions
2016 · Oncogene · 145 citations
https://doi.org/10.1038/onc.2016.243
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Ádám Póti
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Ádám Póti is an academic researcher from HUN-REN Research Centre for Natural Sciences. The author has contributed to research in topics: DNA Repair Mechanisms & Cancer Genomics and Diagnostics & Molecular Biology Techniques and Applications. The author has an h-index of 18, co-authored 46 publications.
ORCID: 0000-0003-2415-6790Papers by this author
worksCorrelation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents
2019 · Genome biology · 118 citations
https://doi.org/10.1186/s13059-019-1867-0
BRCA1 deficiency specific base substitution mutagenesis is dependent on translesion synthesis and regulated by 53BP1
2022 · Nature Communications · 41 citations
https://doi.org/10.1038/s41467-021-27872-7
Long-term treatment with the PARP inhibitor niraparib does not increase the mutation load in cell line models and tumour xenografts
2018 · British Journal of Cancer · 27 citations
https://doi.org/10.1038/s41416-018-0312-6
Additional file 1: of A comprehensive survey of the mutagenic impact of common cancer cytotoxics
2016 · Figshare · 0 citations
https://doi.org/10.6084/m9.figshare.c.3602351_d1
Additional file 6: of Fast and accurate mutation detection in whole genome sequences of multiple isogenic samples with IsoMut
2017 · Figshare · 0 citations
https://doi.org/10.6084/m9.figshare.c.3679039_d6
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