Endogenous Retroelements and the Viral Mimicry Response in Cancer Therapy and Cellular Homeostasis
2021 · Cancer Discovery · 179 citations
https://doi.org/10.1158/2159-8290.cd-21-0506
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Charles A. Ishak
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Charles A. Ishak is an academic researcher from University Health Network. The author has contributed to research in topics: Cancer-related Molecular Pathways & Epigenetics and DNA Methylation & Virus-based gene therapy research. The author has an h-index of 15, co-authored 55 publications.
ORCID: 0000-0002-2287-6738Papers by this author
worksHaploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes
2020 · Nature Communications · 42 citations
https://doi.org/10.1038/s41467-020-18483-9
Chronic Viral Mimicry Induction following p53 Loss Promotes Immune Evasion
2025 · Cancer Discovery · 15 citations
https://doi.org/10.1158/2159-8290.cd-24-0094
Inhibiting EZH2 targets atypical teratoid rhabdoid tumor by triggering viral mimicry via both RNA and DNA sensing pathways
2024 · Nature Communications · 8 citations
https://doi.org/10.1038/s41467-024-53515-8
Figure S4 from Chronic Viral Mimicry Induction following p53 Loss Promotes Immune Evasion
2025 · 0 citations
https://doi.org/10.1158/2159-8290.28713515
Data from Chronic Viral Mimicry Induction following p53 Loss Promotes Immune Evasion
2025 · 0 citations
https://doi.org/10.1158/2159-8290.c.7749821
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