https://doi.org/10.1126/science.1141478
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Pasi A. Jänne
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Pasi A. Jänne is an academic researcher from Harvard University. The author has contributed to research in topics: Lung Cancer Treatments and Mutations & Cancer Genomics and Diagnostics & Colorectal Cancer Treatments and Studies. The author has an h-index of 163, co-authored 1988 publications.
ORCID: 0000-0002-7821-4928Papers by this author
works<i>MET</i> Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
2007 · Science · 4,427 citations
Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints
2016 · Nature Communications · 1,522 citations
https://doi.org/10.1038/ncomms10501
The KRASG12C Inhibitor MRTX849 Provides Insight toward Therapeutic Susceptibility of KRAS-Mutant Cancers in Mouse Models and Patients
2019 · Cancer Discovery · 1,249 citations
https://doi.org/10.1158/2159-8290.cd-19-1167
LKB1 modulates lung cancer differentiation and metastasis
2007 · Nature · 1,060 citations
https://doi.org/10.1038/nature06030
Trastuzumab Deruxtecan in <i>HER2</i> -Mutant Non–Small-Cell Lung Cancer
2021 · New England Journal of Medicine · 911 citations
https://doi.org/10.1056/nejmoa2112431
Adagrasib in Non–Small-Cell Lung Cancer Harboring a <i> KRAS <sup>G12C</sup> </i> Mutation
2022 · New England Journal of Medicine · 886 citations
https://doi.org/10.1056/nejmoa2204619
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