Somatic coding mutations in human induced pluripotent stem cells
2011 · Nature · 1,241 citations
https://doi.org/10.1038/nature09805
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Jessica E. Young
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Jessica E. Young is an academic researcher from University of Washington. The author has contributed to research in topics: Alzheimer's disease research and treatments & Cellular transport and secretion & Neuroinflammation and Neurodegeneration Mechanisms. The author has an h-index of 26, co-authored 99 publications.
ORCID: 0000-0003-2106-0339Papers by this author
worksThe Presenilin-1 ΔE9 Mutation Results in Reduced γ-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells
2013 · Cell Reports · 182 citations
https://doi.org/10.1016/j.celrep.2013.10.018
Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing
2020 · Cell Reports · 151 citations
https://doi.org/10.1016/j.celrep.2020.107719
Human microglia show unique transcriptional changes in Alzheimer’s disease
2023 · Nature Aging · 140 citations
https://doi.org/10.1038/s43587-023-00424-y
Nutrient Deprivation Induces Neuronal Autophagy and Implicates Reduced Insulin Signaling in Neuroprotective Autophagy Activation
2008 · Journal of Biological Chemistry · 126 citations
https://doi.org/10.1074/jbc.m806088200
The Alzheimer’s gene SORL1 is a regulator of endosomal traffic and recycling in human neurons
2022 · Cellular and Molecular Life Sciences · 119 citations
https://doi.org/10.1007/s00018-022-04182-9
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