SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate
2020 · Nature Communications · 450 citations
https://doi.org/10.1038/s41467-020-18764-3
J
John Hiscott
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John Hiscott is an academic researcher from Istituto di Sessuologia Clinica. The author has contributed to research in topics: interferon and immune responses & Cytokine Signaling Pathways and Interactions & NF-κB Signaling Pathways. The author has an h-index of 85, co-authored 344 publications.
ORCID: 0000-0003-2076-6321Papers by this author
worksCrosstalk between Cytoplasmic RIG-I and STING Sensing Pathways
2017 · Trends in Immunology · 350 citations
https://doi.org/10.1016/j.it.2016.12.004
The Mitochondrial Proteins NLRX1 and TUFM Form a Complex that Regulates Type I Interferon and Autophagy
2012 · Immunity · 293 citations
https://doi.org/10.1016/j.immuni.2012.03.025
Phosphorylation of IκBα in the C-Terminal PEST Domain by Casein Kinase II Affects Intrinsic Protein Stability
1996 · Molecular and Cellular Biology · 196 citations
https://doi.org/10.1128/mcb.16.4.1401
Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity
2017 · Molecular Therapy · 79 citations
https://doi.org/10.1016/j.ymthe.2017.04.022
Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression.
2006 · Virology Journal · 73 citations
https://doi.org/10.1186/1743-422x-3-66
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