KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism
2018 · Cancer Cell · 186 citations
https://doi.org/10.1016/j.ccell.2018.10.001
T
Thomas S.K. Gilbert
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Thomas S.K. Gilbert is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: Mitochondrial Function and Pathology & Cancer, Hypoxia, and Metabolism & RNA modifications and cancer. The author has an h-index of 16, co-authored 56 publications.
ORCID: 0000-0002-6833-6788Papers by this author
worksLow-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
2020 · Cell Reports · 97 citations
https://doi.org/10.1016/j.celrep.2020.107764
Kinome Profiling Identifies Druggable Targets for Novel Human Cytomegalovirus (HCMV) Antivirals
2017 · Molecular & Cellular Proteomics · 30 citations
https://doi.org/10.1074/mcp.m116.065375
Mass spectrometry–based selectivity profiling identifies a highly selective inhibitor of the kinase MELK that delays mitotic entry in cancer cells
2020 · Journal of Biological Chemistry · 28 citations
https://doi.org/10.1074/jbc.ra119.011083
The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer
2021 · Journal of Biological Chemistry · 28 citations
https://doi.org/10.1016/j.jbc.2021.101335
A multi-kinase inhibitor screen identifies inhibitors preserving stem-cell-like chimeric antigen receptor T cells
2025 · Nature Immunology · 6 citations
https://doi.org/10.1038/s41590-024-02042-1
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