Patterns of genomic loss of heterozygosity predict homologous recombination repair defects in epithelial ovarian cancer
2012 · British Journal of Cancer · 831 citations
https://doi.org/10.1038/bjc.2012.451
K
Kirsten M. Timms
Myriad (Germany)(DE)
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Kirsten M. Timms is an academic researcher from Myriad (Germany). The author has contributed to research in topics: PARP inhibition in cancer therapy & DNA Repair Mechanisms & BRCA gene mutations in cancer. The author has an h-index of 44, co-authored 149 publications.
ORCID: 0000-0003-4923-2518Papers by this author
worksAssociation of BRCA1/2defects with genomic scores predictive of DNA damage repair deficiency among breast cancer subtypes
2014 · Breast Cancer Research · 416 citations
https://doi.org/10.1186/s13058-014-0475-x
Homologous Recombination Deficiency: Concepts, Definitions, and Assays
2022 · The Oncologist · 207 citations
https://doi.org/10.1093/oncolo/oyab053
Impact of homologous recombination deficiency biomarkers on outcomes in patients with triple-negative breast cancer treated with adjuvant doxorubicin and cyclophosphamide (SWOG S9313)
2017 · Annals of Oncology · 135 citations
https://doi.org/10.1093/annonc/mdx821
Biomarker Assessment of HR Deficiency, Tumor <i>BRCA1/2</i> Mutations, and <i>CCNE1</i> Copy Number in Ovarian Cancer: Associations with Clinical Outcome Following Platinum Monotherapy
2018 · Molecular Cancer Research · 126 citations
https://doi.org/10.1158/1541-7786.mcr-18-0034
A phase II study of talazoparib monotherapy in patients with wild-type BRCA1 and BRCA2 with a mutation in other homologous recombination genes
2022 · Nature Cancer · 124 citations
https://doi.org/10.1038/s43018-022-00439-1
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