Pharmacological targeting of the pseudokinase Her3
2014 · Nature Chemical Biology · 197 citations
https://doi.org/10.1038/nchembio.1658
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Kenneth D. Westover
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Kenneth D. Westover is an academic researcher from The University of Texas Southwestern Medical Center. The author has contributed to research in topics: Lung Cancer Diagnosis and Treatment & Protein Kinase Regulation and GTPase Signaling & Lung Cancer Treatments and Mutations. The author has an h-index of 49, co-authored 248 publications.
ORCID: 0000-0003-3653-5923Papers by this author
worksDirect Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin Signaling
2016 · Cell Reports · 155 citations
https://doi.org/10.1016/j.celrep.2016.05.071
Discovery of Type II Inhibitors of TGFβ-Activated Kinase 1 (TAK1) and Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2)
2014 · Journal of Medicinal Chemistry · 71 citations
https://doi.org/10.1021/jm500480k
KRAS Switch Mutants D33E and A59G Crystallize in the State 1 Conformation
2017 · Biochemistry · 53 citations
https://doi.org/10.1021/acs.biochem.7b00974
Structure-Based Design of a Potent and Selective Covalent Inhibitor for SRC Kinase That Targets a P-Loop Cysteine
2020 · Journal of Medicinal Chemistry · 35 citations
https://doi.org/10.1021/acs.jmedchem.9b01502
Structural basis of the atypical activation mechanism of KRASV14I
2019 · Journal of Biological Chemistry · 33 citations
https://doi.org/10.1074/jbc.ra119.009131
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