The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-Hydroxyglutarate
2010 · Cancer Cell · 1,966 citations
https://doi.org/10.1016/j.ccr.2010.01.020
A
Alexander E. Perl
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Alexander E. Perl is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Acute Myeloid Leukemia Research & Chronic Myeloid Leukemia Treatments & Chronic Lymphocytic Leukemia Research. The author has an h-index of 55, co-authored 351 publications.
ORCID: 0000-0002-1463-2231Papers by this author
worksNCCN Guidelines Insights: Acute Myeloid Leukemia, Version 2.2021
2021 · Journal of the National Comprehensive Cancer Network · 314 citations
https://doi.org/10.6004/jnccn.2021.0002
Gilteritinib as Post-Transplant Maintenance for AML With Internal Tandem Duplication Mutation of <i>FLT3</i>
2024 · Journal of Clinical Oncology · 167 citations
https://doi.org/10.1200/jco.23.02474
Gilteritinib as Post-Transplant Maintenance for AML With Internal Tandem Duplication Mutation of <i>FLT3</i>
2024 · Journal of Clinical Oncology · 167 citations
https://doi.org/10.1200/jco.23.02474
Follow-up of patients with R/R <i>FLT3-</i>mutation–positive AML treated with gilteritinib in the phase 3 ADMIRAL trial
2022 · Blood · 134 citations
https://doi.org/10.1182/blood.2021011583
Dynamic evolution of clonal epialleles revealed by methclone
2014 · Genome biology · 77 citations
https://doi.org/10.1186/s13059-014-0472-5
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