Combining NGN2 Programming with Developmental Patterning Generates Human Excitatory Neurons with NMDAR-Mediated Synaptic Transmission
2018 · Cell Reports · 267 citations
https://doi.org/10.1016/j.celrep.2018.04.066
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Ralda Nehme
Broad Institute(US)
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Ralda Nehme is an academic researcher from Broad Institute. The author has contributed to research in topics: CRISPR and Genetic Engineering & Single-cell and spatial transcriptomics & Pluripotent Stem Cells Research. The author has an h-index of 20, co-authored 49 publications.
ORCID: 0000-0001-7215-3311Papers by this author
worksNatural variation in gene expression and viral susceptibility revealed by neural progenitor cell villages
2023 · Cell stem cell · 101 citations
https://doi.org/10.1016/j.stem.2023.01.010
Brain Chimeroids reveal individual susceptibility to neurotoxic triggers
2024 · Nature · 73 citations
https://doi.org/10.1038/s41586-024-07578-8
Simultaneous CRISPR screening and spatial transcriptomics reveal intracellular, intercellular, and functional transcriptional circuits
2025 · Cell · 55 citations
https://doi.org/10.1016/j.cell.2025.02.012
Efficient generation of lower induced motor neurons by coupling Ngn2 expression with developmental cues
2023 · Cell Reports · 45 citations
https://doi.org/10.1016/j.celrep.2022.111896
Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neurons
2023 · Cell Reports · 30 citations
https://doi.org/10.1016/j.celrep.2022.111988
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