Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations
2018 · Nature Genetics · 2,994 citations
https://doi.org/10.1038/s41588-018-0183-z
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Amit V. Khera
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Amit V. Khera is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Genetic Associations and Epidemiology & Lipoproteins and Cardiovascular Health & Diabetes, Cardiovascular Risks, and Lipoproteins. The author has an h-index of 64, co-authored 254 publications.
ORCID: 0000-0001-6535-5839Papers by this author
worksA saturated map of common genetic variants associated with human height
2022 · Nature · 848 citations
https://doi.org/10.1038/s41586-022-05275-y
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants
2022 · Nature Genetics · 648 citations
https://doi.org/10.1038/s41588-022-01233-6
Exome-wide association study of plasma lipids in >300,000 individuals
2017 · Nature Genetics · 589 citations
https://doi.org/10.1038/ng.3977
Lp(a) (Lipoprotein[a]) Concentrations and Incident Atherosclerotic Cardiovascular Disease
2020 · Arteriosclerosis Thrombosis and Vascular Biology · 485 citations
https://doi.org/10.1161/atvbaha.120.315291
Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions
2020 · Nature Communications · 464 citations
https://doi.org/10.1038/s41467-020-17374-3
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