High thermal stability is essential for tumor targeting of antibody fragments: engineering of a humanized anti-epithelial glycoprotein-2 (epithelial cell adhesion molecule) single-chain Fv fragment.
1999 · PubMed · 201 citations
A
Annemarie Honegger
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Annemarie Honegger is an academic researcher from École Normale Supérieure de Lyon. The author has contributed to research in topics: Monoclonal and Polyclonal Antibodies Research & Glycosylation and Glycoproteins Research & Protein purification and stability. The author has an h-index of 54, co-authored 91 publications.
ORCID: 0000-0002-3378-3967Papers by this author
worksA Tyrosine-Phosphorylated Carboxy-Terminal Peptide of the Fibroblast Growth Factor Receptor (Flg) Is a Binding Site for the SH2 Domain of Phospholipase C-γ1
1991 · Molecular and Cellular Biology · 99 citations
https://doi.org/10.1128/mcb.11.10.5068-5078.1991
Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control
2018 · Nature Communications · 94 citations
https://doi.org/10.1038/s41467-017-02707-6
Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters
2013 · Proceedings of the National Academy of Sciences · 87 citations
https://doi.org/10.1073/pnas.1213653110
Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action
2021 · Nature Communications · 59 citations
https://doi.org/10.1038/s41467-021-23948-6
Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts
2019 · Scientific Reports · 16 citations
https://doi.org/10.1038/s41598-019-52121-9
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