Inhibition of IL-11 signalling extends mammalian healthspan and lifespan
2024 · Nature · 193 citations
https://doi.org/10.1038/s41586-024-07701-9
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Anissa A. Widjaja
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Anissa A. Widjaja is an academic researcher from Duke-NUS Medical School. The author has contributed to research in topics: Liver Disease Diagnosis and Treatment & Cytokine Signaling Pathways and Interactions & Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis. The author has an h-index of 26, co-authored 57 publications.
ORCID: 0000-0001-9404-7608Papers by this author
worksSpermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression
2022 · Nature Communications · 80 citations
https://doi.org/10.1038/s41467-022-32788-x
Targeting endogenous kidney regeneration using anti-IL11 therapy in acute and chronic models of kidney disease
2022 · Nature Communications · 70 citations
https://doi.org/10.1038/s41467-022-35306-1
Molecular Dissection of Pro-Fibrotic IL11 Signaling in Cardiac and Pulmonary Fibroblasts
2021 · Frontiers in Molecular Biosciences · 52 citations
https://doi.org/10.3389/fmolb.2021.740650
Similarities and differences between IL11 and IL11RA1 knockout mice for lung fibro-inflammation, fertility and craniosynostosis
2021 · Scientific Reports · 44 citations
https://doi.org/10.1038/s41598-021-93623-9
Antibody‐mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload
2021 · Clinical and Experimental Pharmacology and Physiology · 16 citations
https://doi.org/10.1111/1440-1681.13458
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