Plant lectins are potent inhibitors of coronaviruses by interfering with two targets in the viral replication cycle
2007 · Antiviral Research · 295 citations
https://doi.org/10.1016/j.antiviral.2007.03.003
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Christophe Pannecouque
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Christophe Pannecouque is an academic researcher from Rega Institute for Medical Research. The author has contributed to research in topics: HIV/AIDS drug development and treatment & HIV Research and Treatment & Click Chemistry and Applications. The author has an h-index of 71, co-authored 642 publications.
ORCID: 0000-0002-1254-4473Papers by this author
worksOverview of Recent Strategic Advances in Medicinal Chemistry
2019 · Journal of Medicinal Chemistry · 177 citations
https://doi.org/10.1021/acs.jmedchem.9b00359
Medicinal chemistry strategies for discovering antivirals effective against drug-resistant viruses
2021 · Chemical Society Reviews · 176 citations
https://doi.org/10.1039/d0cs01084g
Design, Synthesis, and Evaluation of Thiophene[3,2-<i>d</i>]pyrimidine Derivatives as HIV-1 Non-nucleoside Reverse Transcriptase Inhibitors with Significantly Improved Drug Resistance Profiles
2016 · Journal of Medicinal Chemistry · 134 citations
https://doi.org/10.1021/acs.jmedchem.6b00738
Identification of Dihydrofuro[3,4-<i>d</i>]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties
2019 · Journal of Medicinal Chemistry · 86 citations
https://doi.org/10.1021/acs.jmedchem.8b01656
Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles
2019 · Journal of Medicinal Chemistry · 76 citations
https://doi.org/10.1021/acs.jmedchem.8b01729
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