Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice
2020 · Science Translational Medicine · 197 citations
https://doi.org/10.1126/scitranslmed.aay1163
A
Annie Arguello
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10
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Annie Arguello is an academic researcher from Denali Therapeutics (United States). The author has contributed to research in topics: Lysosomal Storage Disorders Research & Cellular transport and secretion & Trypanosoma species research and implications. The author has an h-index of 10, co-authored 27 publications.
ORCID: 0000-0002-0313-0041Papers by this author
worksDecreased lipidated ApoE-receptor interactions confer protection against pathogenicity of ApoE and its lipid cargoes in lysosomes
2024 · Cell · 67 citations
https://doi.org/10.1016/j.cell.2024.10.027
High-Throughput Liquid Chromatography–Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II
2020 · International Journal of Molecular Sciences · 18 citations
https://doi.org/10.3390/ijms21155449
Lysosomal polyamine storage upon ATP13A2 loss impairs β-glucocerebrosidase via altered lysosomal pH and electrostatic hydrolase-lipid interactions
2025 · Cell Reports · 5 citations
https://doi.org/10.1016/j.celrep.2025.116179
ETV:SGSH, a brain-penetrant enzyme transport vehicle for SGSH, improves lysosomal and microglial morphology, degeneration and cognitive behavior in MPS IIIA mice
2024 · Molecular Genetics and Metabolism · 0 citations
https://doi.org/10.1016/j.ymgme.2023.107954
219 MACROPHAGE LRRK2 HYPERACTIVITY IMPAIRS AUTOPHAGY AND INDUCES PANETH CELL DYSFUNCTION AND INTESTINAL INFLAMMATION
2024 · Gastroenterology · 0 citations
https://doi.org/10.1016/s0016-5085(24)00599-7
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