Kinase inhibitors modulate huntingtin cell localization and toxicity
2011 · Nature Chemical Biology · 243 citations
https://doi.org/10.1038/nchembio.582
N
Nicholas S. Caron
Claim or correct this author profile
Claim this profile or suggest corrections to the name, affiliation, bio, photo, or paper titles. Approved changes appear as verified CitedEvidence overlays.
68
Papers
2.2K
Citations
25
h-index
32
i10-index
Nicholas S. Caron is an academic researcher from University of British Columbia. The author has contributed to research in topics: Genetic Neurodegenerative Diseases & Mitochondrial Function and Pathology & Neurological disorders and treatments. The author has an h-index of 25, co-authored 58 publications.
ORCID: 0000-0002-3877-455XPapers by this author
worksUltrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression
2015 · Scientific Reports · 105 citations
https://doi.org/10.1038/srep12166
Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease
2018 · Acta Neuropathologica Communications · 76 citations
https://doi.org/10.1186/s40478-018-0518-0
Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
2016 · Scientific Reports · 66 citations
https://doi.org/10.1038/srep31652
Frequency of the loss of CAA interruption in the HTT CAG tract and implications for Huntington disease in the reduced penetrance range
2020 · Genetics in Medicine · 50 citations
https://doi.org/10.1038/s41436-020-0917-z
Rescue of aberrant huntingtin palmitoylation ameliorates mutant huntingtin-induced toxicity
2021 · Neurobiology of Disease · 32 citations
https://doi.org/10.1016/j.nbd.2021.105479
Research topics
topicsChat about Author
Papers
Chat
Click to start Chat