Acute MeCP2 loss in adult mice reveals transcriptional and chromatin changes that precede neurological dysfunction and inform pathogenesis
2024 · Neuron · 22 citations
https://doi.org/10.1016/j.neuron.2024.11.006
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Harini P Tirumala
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Harini P Tirumala is an academic researcher from Neurological Research Institute. The author has contributed to research in topics: Genetics and Neurodevelopmental Disorders & Mitochondrial Function and Pathology & Chromatin Remodeling and Cancer. The author has an h-index of 4, co-authored 6 publications.
ORCID: 0000-0002-1318-2072Papers by this author
worksIdentification and characterization of conserved noncoding <i>cis</i>-regulatory elements that impact <i>Mecp2</i> expression and neurological functions
2021 · Genes & Development · 16 citations
https://doi.org/10.1101/gad.345397.120
Modeling antisense oligonucleotide therapy in <i>MECP2</i> duplication syndrome human iPSC-derived neurons reveals gene expression programs responsive to MeCP2 levels
2024 · Human Molecular Genetics · 9 citations
https://doi.org/10.1093/hmg/ddae135
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