Targeting DNA damage response pathways in cancer
2022 · Nature reviews. Cancer · 778 citations
https://doi.org/10.1038/s41568-022-00535-5
F
Florian J. Groelly
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Florian J. Groelly is an academic researcher from University of Oxford. The author has contributed to research in topics: DNA Repair Mechanisms & CRISPR and Genetic Engineering & interferon and immune responses. The author has an h-index of 6, co-authored 8 publications.
ORCID: 0000-0001-7699-7108Papers by this author
worksBRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors
2019 · Nature Communications · 180 citations
https://doi.org/10.1038/s41467-019-11048-5
Mitotic DNA synthesis is caused by transcription-replication conflicts in BRCA2-deficient cells
2022 · Molecular Cell · 49 citations
https://doi.org/10.1016/j.molcel.2022.07.011
Anti‐tumoural activity of the G‐quadruplex ligand pyridostatin against BRCA1/2‐deficient tumours
2022 · EMBO Molecular Medicine · 43 citations
https://doi.org/10.15252/emmm.202114501
A transcription-based mechanism for oncogenic β-catenin-induced lethality in BRCA1/2-deficient cells
2021 · Nature Communications · 11 citations
https://doi.org/10.1038/s41467-021-25215-0
High-resolution mapping of mitotic DNA synthesis under conditions of replication stress in cultured cells
2023 · STAR Protocols · 1 citations
https://doi.org/10.1016/j.xpro.2022.101970
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