Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures
2018 · Nature Communications · 214 citations
https://doi.org/10.1038/s41467-017-02533-w
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Sabrina Simoes
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Sabrina Simoes is an academic researcher from Columbia University Irving Medical Center. The author has contributed to research in topics: Alzheimer's disease research and treatments & Cellular transport and secretion & Dementia and Cognitive Impairment Research. The author has an h-index of 16, co-authored 30 publications.
ORCID: 0000-0002-9976-2501Papers by this author
worksAlzheimer's vulnerable brain region relies on a distinct retromer core dedicated to endosomal recycling
2021 · Cell Reports · 62 citations
https://doi.org/10.1016/j.celrep.2021.110182
The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease
2022 · Cell Reports · 36 citations
https://doi.org/10.1016/j.celrep.2021.110262
Juvenile CLN3 disease is a lysosomal cholesterol storage disorder: similarities with Niemann-Pick type C disease
2023 · EBioMedicine · 9 citations
https://doi.org/10.1016/j.ebiom.2023.104628
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