Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3
2015 · Nature Communications · 429 citations
https://doi.org/10.1038/ncomms7656
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Sadhana Samant
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Sadhana Samant is an academic researcher from University of Chicago. The author has contributed to research in topics: Sirtuins and Resveratrol in Medicine & Adipose Tissue and Metabolism & Mitochondrial Function and Pathology. The author has an h-index of 25, co-authored 49 publications.
ORCID: 0000-0001-9647-6692Papers by this author
worksSIRT3 Deacetylates and Activates OPA1 To Regulate Mitochondrial Dynamics during Stress
2013 · Molecular and Cellular Biology · 419 citations
https://doi.org/10.1128/mcb.01483-13
SIRT1 Promotes Cell Survival under Stress by Deacetylation-Dependent Deactivation of Poly(ADP-Ribose) Polymerase 1
2009 · Molecular and Cellular Biology · 296 citations
https://doi.org/10.1128/mcb.00121-09
Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice
2017 · Oncotarget · 190 citations
https://doi.org/10.18632/oncotarget.16133
Sirt3 protects mitochondrial DNA damage and blocks the development of doxorubicin-induced cardiomyopathy in mice
2016 · American Journal of Physiology-Heart and Circulatory Physiology · 146 citations
https://doi.org/10.1152/ajpheart.00832.2015
The nuclear and mitochondrial sirtuins, Sirt6 and Sirt3, regulate each other's activity and protect the heart from developing obesity‐mediated diabetic cardiomyopathy
2019 · The FASEB Journal · 94 citations
https://doi.org/10.1096/fj.201900767r
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