Neurotoxic reactive astrocytes are induced by activated microglia
2017 · Nature · 7,642 citations
https://doi.org/10.1038/nature21029
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Christopher J. Bohlen
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Christopher J. Bohlen is an academic researcher from Neurological Surgery. The author has contributed to research in topics: Neuroinflammation and Neurodegeneration Mechanisms & Ion channel regulation and function & Immune cells in cancer. The author has an h-index of 21, co-authored 37 publications.
ORCID: 0000-0003-1185-2260Papers by this author
worksNew tools for studying microglia in the mouse and human CNS
2016 · Proceedings of the National Academy of Sciences · 1,810 citations
https://doi.org/10.1073/pnas.1525528113
Loss of μ opioid receptor signaling in nociceptors, but not microglia, abrogates morphine tolerance without disrupting analgesia
2017 · Nature Medicine · 336 citations
https://doi.org/10.1038/nm.4262
Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology
2021 · Neuron · 330 citations
https://doi.org/10.1016/j.neuron.2021.02.010
Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia
2019 · Cell Reports · 224 citations
https://doi.org/10.1016/j.celrep.2019.05.010
Rapid affinity optimization of an anti-TREM2 clinical lead antibody by cross-lineage immune repertoire mining
2024 · Nature Communications · 7 citations
https://doi.org/10.1038/s41467-024-52442-y
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