A New Class of Potent<i>N</i>-Methyl-<scp>d</scp>-Aspartate Receptor Inhibitors: Sulfated Neuroactive Steroids with Lipophilic D-Ring Modifications
2015 · Journal of Medicinal Chemistry · 32 citations
https://doi.org/10.1021/acs.jmedchem.5b00570
M
Michaela Nekardová
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10
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Michaela Nekardová is an academic researcher from Czech Academy of Sciences, Institute of Biotechnology. The author has contributed to research in topics: Neuroscience and Neuropharmacology Research & Receptor Mechanisms and Signaling & Estrogen and related hormone effects. The author has an h-index of 10, co-authored 11 publications.
ORCID: 0000-0001-5810-7650Papers by this author
worksPositive Modulators of the<i>N</i>-Methyl-<scp>d</scp>-aspartate Receptor: Structure–Activity Relationship Study of Steroidal 3-Hemiesters
2018 · Journal of Medicinal Chemistry · 27 citations
https://doi.org/10.1021/acs.jmedchem.8b00255
Physicochemical and biological properties of novel amide-based steroidal inhibitors of NMDA receptors
2016 · Steroids · 26 citations
https://doi.org/10.1016/j.steroids.2016.08.010
Neurosteroid-like Inhibitors of<i>N</i>-Methyl-<scp>d</scp>-aspartate Receptor: Substituted 2-Sulfates and 2-Hemisuccinates of Perhydrophenanthrene
2016 · Journal of Medicinal Chemistry · 17 citations
https://doi.org/10.1021/acs.jmedchem.6b00079
Structural Basis of the Interaction of Cyclin‐Dependent Kinase 2 with Roscovitine and Its Analogues Having Bioisosteric Central Heterocycles
2017 · ChemPhysChem · 16 citations
https://doi.org/10.1002/cphc.201601319
Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of N-Methyl-D-Aspartate Receptors With C-3 Amide Structural Motif
2018 · Frontiers in Pharmacology · 11 citations
https://doi.org/10.3389/fphar.2018.01299
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