A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
2015 · Nature Medicine · 2,700 citations
https://doi.org/10.1038/nm.3806
S
Seth L. Masters
Claim or correct this author profile
Claim this profile or suggest corrections to the name, affiliation, bio, photo, or paper titles. Approved changes appear as verified CitedEvidence overlays.
202
Papers
28.4K
Citations
68
h-index
124
i10-index
Seth L. Masters is an academic researcher from Walter and Eliza Hall Institute of Medical Research. The author has contributed to research in topics: Inflammasome and immune disorders & interferon and immune responses & Immune Response and Inflammation. The author has an h-index of 68, co-authored 172 publications.
ORCID: 0000-0003-4763-576XPapers by this author
worksTDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS
2020 · Cell · 940 citations
https://doi.org/10.1016/j.cell.2020.09.020
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL
2015 · Nature Communications · 624 citations
https://doi.org/10.1038/ncomms7282
Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism
2018 · Cell Metabolism · 431 citations
https://doi.org/10.1016/j.cmet.2018.03.014
TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
2020 · Cell Reports · 418 citations
https://doi.org/10.1016/j.celrep.2020.03.056
Constitutive immune mechanisms: mediators of host defence and immune regulation
2020 · Nature reviews. Immunology · 342 citations
https://doi.org/10.1038/s41577-020-0391-5
Research topics
topicsChat about Author
Papers
Chat
Click to start Chat