Structure-based discovery of nonopioid analgesics acting through the α <sub>2A</sub> -adrenergic receptor
2022 · Science · 146 citations
https://doi.org/10.1126/science.abn7065
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Jun Xu
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Jun Xu is an academic researcher from University of Science and Technology. The author has contributed to research in topics: Receptor Mechanisms and Signaling & Protein Kinase Regulation and GTPase Signaling & Peroxisome Proliferator-Activated Receptors. The author has an h-index of 35, co-authored 92 publications.
ORCID: 0000-0002-1600-583XPapers by this author
worksStructural mechanism underlying primary and secondary coupling between GPCRs and the Gi/o family
2020 · Nature Communications · 74 citations
https://doi.org/10.1038/s41467-020-16975-2
Insulin Resistance in Striated Muscle-specific Integrin Receptor β1-deficient Mice
2008 · Journal of Biological Chemistry · 61 citations
https://doi.org/10.1074/jbc.m807408200
Activation and allosteric regulation of the orphan GPR88-Gi1 signaling complex
2022 · Nature Communications · 41 citations
https://doi.org/10.1038/s41467-022-30081-5
Structure and function of a near fully-activated intermediate GPCR-Gαβγ complex
2025 · Nature Communications · 8 citations
https://doi.org/10.1038/s41467-025-56434-4
Mechanism and function of GPR3 regulated by a negative allosteric modulator
2025 · Nature Communications · 2 citations
https://doi.org/10.1038/s41467-025-63422-1
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