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Martina S.J. McDermott

University of California, Los Angeles(US)

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208

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1.4K

Citations

17

h-index

20

i10-index

Martina S.J. McDermott is an academic researcher from University of California, Los Angeles. The author has contributed to research in topics: HER2/EGFR in Cancer Research & Monoclonal and Polyclonal Antibodies Research & Advanced Breast Cancer Therapies. The author has an h-index of 17, co-authored 177 publications.

ORCID: 0000-0001-5737-7202

Research Topics

HER2/EGFR in Cancer Research Monoclonal and Polyclonal Antibodies Research Advanced Breast Cancer Therapies Radiopharmaceutical Chemistry and Applications Glycosylation and Glycoproteins Research

Papers by this author

works

Targeting activated PI3K/mTOR signaling overcomes acquired resistance to CDK4/6-based therapies in preclinical models of hormone receptor-positive breast cancer

2020 · Breast Cancer Research · 150 citations

https://doi.org/10.1186/s13058-020-01320-8

Neil A. O’Brien Martina S.J. McDermott Dylan Conklin Tong Luo

Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo

2022 · Proceedings of the National Academy of Sciences · 50 citations

https://doi.org/10.1073/pnas.2201073119

Xiaokai Ding Amanda C. Sharko Martina S.J. McDermott Gary P. Schools

PP2A inhibition overcomes acquired resistance to HER2 targeted therapy

2014 · Molecular Cancer · 42 citations

https://doi.org/10.1186/1476-4598-13-157

Martina S.J. McDermott Brigid C. Browne Neil T. Conlon Neil A. O’Brien

Dual inhibition of IGF1R and ER enhances response to trastuzumab in HER2 positive breast cancer cells

2017 · International Journal of Oncology · 41 citations

https://doi.org/10.3892/ijo.2017.3976

Martina S.J. McDermott Alexandra Canonici Laura Ivers Brigid C. Browne

Evaluation of IGF1R and phosphorylated IGF1R as targets in HER2-positive breast cancer cell lines and tumours

2012 · Breast Cancer Research and Treatment · 37 citations

https://doi.org/10.1007/s10549-012-2260-9

Brigid C. Browne Alex J. Eustace Susan Kennedy Neil A. O’Brien

Alterations in immune cell phenotype and cytotoxic capacity in HER2+ breast cancer patients receiving HER2-targeted neo-adjuvant therapy

2023 · British Journal of Cancer · 12 citations

https://doi.org/10.1038/s41416-023-02375-y

Nicola Gaynor Alfonso Blanco Stephen F. Madden Barry Moran

Research topics

topics

HER2/EGFR in Cancer Research

Monoclonal and Polyclonal Antibodies Research

Advanced Breast Cancer Therapies

Radiopharmaceutical Chemistry and Applications

Glycosylation and Glycoproteins Research

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