Abstract 9612: Does quantification of Epicardial Adipose Tissue (EATv) and Intrathoracic Fat (ITFv) Volume with Noncontrast Cardiac Computed Tomography (CCT) improve Coronary Events (CE) Prediction Over Clinical Information and Coronary Artery Calcium Score (CACS)?

TL;DRAbstract

Background: CCT allows for calculation of CACS and measurement of EATv and ITFv. It is unclear whether EATv and ITFv provide additional value over CACS and clinical information in predicting CE. Methods: 760 consecutive symptomatic patients without known coronary disease underwent CCT and were followed up to 5 years (median 3.3 years) for CE (cardiac death, non fatal MI, and acute coronary syndrome with >70% coronary artery stenosis). The mean age was 54.4 ±13.7 years, 60 % were female, 15% were diabetics, mean body mass index (BMI) of 30.6 kg/m 2 and mean Framingham risk score (FRS) of 8.2. The ITFv and EATv were calculated with semiautomated method. Fat tissue were automatically recognized by threshold between -40 and-200 HU. Results: Compared to 715 event-free patients, the 45 patients who had CE were older (64.8 vs 53.7 y/o p<0.001), more male (60% vs 40% p=0.008), higher mean FRS (14.3 vs 7.8 p<0.001) and higher median CACS (268 vs 0 p <0.001). They also had higher med

Chat with Paper

AI Agents for this Paper