Plasminogen Activator Inhibitor-2 Plays a Leading Prognostic Role among Protease Families in Non-Small Cell Lung Cancer
Chia‐Yi Su,Yu‐Peng Liu,Chih‐Jen Yang,Yuan‐Feng Lin,Jean Chiou,Li-Hsing Chi+5 more-2015-07-31-PLoS ONE
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TL;DRAbstract
We revealed PAI-2 as the most powerful prognostic marker among PA and MMP protease family even after considering their close relationships with each other. By utilizing a combination of PAI-2 and MMP-9, more precise prognostic information than merely using pathological stage alone can be obtained for lung cancer patients.
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We revealed PAI-2 as the most powerful prognostic marker among PA and MMP protease family even after considering their close relationships with each other. By utilizing a combination of PAI-2 and MMP-9, more precise prognostic information than merely using pathological stage alone can be obtained for lung cancer patients.
Keywords
ImmunohistochemistryLung cancerInternal medicineMedicineOncologyPlasminogen activator inhibitor-1CancerCohort
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