Evidence Live 2015: Basic and clinical pharmacology of the "uroselective" α blocker tamsulosin: a critical analysis.

TL;DRAbstract

<em>Abstract accepted for poster presentation at Evidence Live 2015.</em> -- <strong>Introduction</strong> Tamsulosin is one of the most prescribed urological drugs today and it is also available withoutprescription (over the counter) in some countries (e.g., United Kingdom) despite limited evidence supporting their safety and effectiveness. <strong>Objectives</strong> To determine the safety and effectiveness of tamsulosin in humans. <strong>Methods</strong> 1. Data sources Analysis of tamsulosin studies registered at ClinicalTrials.gov and WHO ICTRP.Analysis of tamsulosin publications (clinical trials, observational studies, systematic reviews and meta-analysis): PubMed, Embase, ISI Web of Knowledge, and other databases. 2. Variables Prospective vs. retrospective registration: time difference between the 1st submission of the study register and start date for the beginning of patient recruitment. Published vs. unpublished studies. Results available at registration site. Types of spon

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