Cognitive Development in Down Syndrome: A Longitudinal Study of Subtest Scores on the Stanford-Binet: Fourth Edition SB:IV

TL;DRAbstract

Down syndrome results when all or part of the 21st chromosome occurs in triplicate at or shortly after conception. Triplication of this chromosome results in small changes in the formation of certain biological structures. Initial structural differences constitute one important influence on development. This thesis explored development of a small number of cognitive abilities across the ages 4 years to 30 years for individuals with Down syndrome using data from the Stanford Binet (fourth edition) (SB:IV) test of intelligence. The approach used in this thesis reflected the understanding that domains underpinning this assessment tool (derived through factor analysis with a general population sample) may not have provided sufficient detail for understanding development for this population. Using the multilevel model for change, growth curves were derived to describe development of abilities at the sub-test level, allowing a more fine grained interpretation of the data. The dataset for thi

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