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Pharmacological and Combined Interventions to Reduce Vaccine Injection Pain in Children and Adults

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TL;DRAbstract

Breastfeeding, topical anesthetics, sweet-tasting solutions, and combination of topical anesthetics and breastfeeding demonstrated evidence of benefit for reducing vaccine injection pain in infants and children. In adults, limited data demonstrate some benefit of topical anesthetics and vapocoolants.

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Breastfeeding, topical anesthetics, sweet-tasting solutions, and combination of topical anesthetics and breastfeeding demonstrated evidence of benefit for reducing vaccine injection pain in infants and children. In adults, limited data demonstrate some benefit of topical anesthetics and vapocoolants.

Keywords

MedicinePlaceboRandomized controlled trialConfidence intervalStrictly standardized mean differenceDistressPsychological interventionPhysical therapy

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