User Settings
Article

Locomotion and Anxiety After Caffeine Intake in HiS and LoS Rats

Jennifer Wang-2012-01-01-Occidental College Scholar (Occidental College)
0

TL;DRAbstract

Caffeine is a widely consumed psychoactive substance, present in many types of comestibles. As a stimulant, caffeine is positively correlated with increased alertness and energy. Caffeine’s arousing effect stems from the blockage of adenosine receptors in the brain, which when blocked, increase neuron firing in the brain and adrenaline production. Caffeine also induces anxiety. During prolonged exposure to caffeine, tolerance develops as an adaptive response; however, removal of the drug may result in a state of emergency.\nThe present research investigated the behavioral effects of caffeine intake and withdrawal with regards to locomotor activity and anxiety in an “open field” apparatus. High-Saccharin- (HiS) and Low-Saccharin-preferring (LoS) rats were used to examine drug effects; their differential consumption of saccharin may influence drug-related behaviors. They have been shown to differ in emotionality, with LoS rats typically displaying more anxiety than HiS rats.\nResults ind

Chat with Paper

AI Agents for this Paper

Caffeine is a widely consumed psychoactive substance, present in many types of comestibles. As a stimulant, caffeine is positively correlated with increased alertness and energy. Caffeine’s arousing effect stems from the blockage of adenosine receptors in the brain, which when blocked, increase neuron firing in the brain and adrenaline production. Caffeine also induces anxiety. During prolonged exposure to caffeine, tolerance develops as an adaptive response; however, removal of the drug may result in a state of emergency.\nThe present research investigated the behavioral effects of caffeine intake and withdrawal with regards to locomotor activity and anxiety in an “open field” apparatus. High-Saccharin- (HiS) and Low-Saccharin-preferring (LoS) rats were used to examine drug effects; their differential consumption of saccharin may influence drug-related behaviors. They have been shown to differ in emotionality, with LoS rats typically displaying more anxiety than HiS rats.\nResults ind

Keywords

CaffeineAnxietyPsychologyMedicinePhysical medicine and rehabilitationSocial psychologyInternal medicinePsychiatry

Chat

Click to start Chat