DNA Mismatch Repair Status Predicts Need for Future Colorectal Surgery for Metachronous Neoplasms in Young Individuals Undergoing Colorectal Cancer Resection

doi:https://doi.org/10.1097/dcr.0000000000000391

DNA Mismatch Repair Status Predicts Need for Future Colorectal Surgery for Metachronous Neoplasms in Young Individuals Undergoing Colorectal Cancer Resection

Melyssa Aronson,Spring Holter,Kara Semotiuk,Laura Winter,Aaron Pollett,Steven Gallinger+2 more-2015-06-07-Diseases of the Colon & Rectum

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TL;DRAbstract

Young patients with colorectal cancer with molecular hallmarks of Lynch syndrome were at significantly higher risk for the development of subsequent colorectal neoplasia. This risk was significantly reduced in those who underwent extended resection compared with segmental resection.

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Young patients with colorectal cancer with molecular hallmarks of Lynch syndrome were at significantly higher risk for the development of subsequent colorectal neoplasia. This risk was significantly reduced in those who underwent extended resection compared with segmental resection.

Keywords

MedicineColorectal cancerInternal medicineSurgical oncologyRetrospective cohort studyOncologyColorectal surgeryUnivariate analysis

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