Capillary electrochromatography of inorganic and small organic anions using pseudo and wall-coated ion exchange phases

TL;DRAbstract

This work presents a systematic study on the use of pseudo-phase and wall-coated ion-exchange (IE) phases for the separation of anions by ion-exchange capillary electrochromatography (IE-CEC). The viability of using open tubular (OT) columns prepared by adsorbing small cationic particles onto the capillary wall for the selectivity manipulation of inorganic anions by IE-CEC was examined. The introduction of an IE component into the separation mechanism allowed the separation selectivity to be varied by changing the type and concentration of the electrolyte anion. This enabled the migration order of a mixture of ions to be changed from a chromatographic selectivity to an electrophoretic selectivity, via novel intermediate selectivities. When separating UV transparent ions, the IE competing ion also acted as the indirect detection probe, which restricted the range over which the concentration could be varied. Selectivity manipulation in this case was achieved by varying the type of probe

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