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Abstract 9111: The Summation of ST-Segment Elevation is a Novel Predictor for Complications in Patients with Stress (Takotsubo) Cardiomyopathy

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Background: Although the prognosis of stress (Takotsubo) cardiomyopathy (SC) is relatively favorable, it sometimes leads to serious complications. It is generally accepted that electrocardiogram (ECG) highly suggestive of the characteristics of myocardial damage is essential tool for diagnosis of SC. We assessed the hypothesis that serial change and quantitative analysis of ECG are associated with following adverse events in patients with SC. Methods and Results: The study patients consisted of 85 patients with SC. A total of 34 patients suffered from 1 or more in-hospital adverse events such as heart failure, intraventricular pressure gradient (>30 mmHg), cardiogenic shock, ventricular tachycardia/fibrillation, and cerebral embolism. Of them, 2 patients died of cardiogenic shock. Patients with adverse events had higher heart rate (96±25 vs. 76±17 bpm, p<0.001) and greater summation of ST-segment elevation in 12 leads (ΣSTE) (10.5 [5.0 to 17.5] mm vs. 3.0 [0 to 7.0] mm; p<0.00

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Background: Although the prognosis of stress (Takotsubo) cardiomyopathy (SC) is relatively favorable, it sometimes leads to serious complications. It is generally accepted that electrocardiogram (ECG) highly suggestive of the characteristics of myocardial damage is essential tool for diagnosis of SC. We assessed the hypothesis that serial change and quantitative analysis of ECG are associated with following adverse events in patients with SC. Methods and Results: The study patients consisted of 85 patients with SC. A total of 34 patients suffered from 1 or more in-hospital adverse events such as heart failure, intraventricular pressure gradient (>30 mmHg), cardiogenic shock, ventricular tachycardia/fibrillation, and cerebral embolism. Of them, 2 patients died of cardiogenic shock. Patients with adverse events had higher heart rate (96±25 vs. 76±17 bpm, p<0.001) and greater summation of ST-segment elevation in 12 leads (ΣSTE) (10.5 [5.0 to 17.5] mm vs. 3.0 [0 to 7.0] mm; p<0.00

Keywords

MedicineCardiomyopathyCardiologyInternal medicineElevation (ballistics)ST segmentST elevationStress testing (software)

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