Article
Chemical conjugation of a novel antibody-interleukin 2 immunoconjugate against c-erbB-2 product.
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TL;DRAbstract
Our method of conjugation of rhIL-2 to 520C9 preserves the binding activity of the antibody and the cytokine function of IL-2. This simple and efficient method of conjugation should be applicable to other types of MoAbs and recombinant cytokines.
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Our method of conjugation of rhIL-2 to 520C9 preserves the binding activity of the antibody and the cytokine function of IL-2. This simple and efficient method of conjugation should be applicable to other types of MoAbs and recombinant cytokines.
Keywords
ImmunoconjugateMonoclonal antibodyChemistryAntibodyInterleukin 2Peripheral blood mononuclear cellConjugateMolecular biology
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