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Article10.1161/circ.128.suppl_22.a18582

Abstract 18582: Left Atrial Mechanics in Heart Failure With Preserved Ejection Fraction: Prognostic Utility of Left Atrial Strain and Tissue Doppler A’ Velocities

Benjamin H. Freed,Frank G. Aguilar,Kameswari Maganti,Michael A. Burke,Sanjiv J. Shah-2013-11-26-Circulation
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TL;DRAbstract

Background: Left atrial (LA) size and function are useful parameters for identifying patients with heart failure and preserved ejection fraction (HFpEF). In HFpEF patients, the prognostic utility of poor LA mechanics (reduced LA strain or reservoir function and/or tissue Doppler imaging [TDI] A’ velocities) has not been explored. We hypothesized that reduced LA strain and A’ velocities are independently associated with adverse outcomes. Methods: We prospectively evaluated LA mechanics in 86 patients with HFpEF. All patients underwent comprehensive echocardiography, including Doppler, TDI, and speckle-tracking analysis. The following measurements were made in all patients: TDI systolic (S’), early diastolic (E’), and late diastolic/atrial (A’) velocities as well as LV global longitudinal (LVGLS), RV free wall (RVFWS), and global longitudinal LA peak positive strain. Patients were followed every 3 months for the composite outcome of heart failure hospitalization, cardiovascular hospitali

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Background: Left atrial (LA) size and function are useful parameters for identifying patients with heart failure and preserved ejection fraction (HFpEF). In HFpEF patients, the prognostic utility of poor LA mechanics (reduced LA strain or reservoir function and/or tissue Doppler imaging [TDI] A’ velocities) has not been explored. We hypothesized that reduced LA strain and A’ velocities are independently associated with adverse outcomes. Methods: We prospectively evaluated LA mechanics in 86 patients with HFpEF. All patients underwent comprehensive echocardiography, including Doppler, TDI, and speckle-tracking analysis. The following measurements were made in all patients: TDI systolic (S’), early diastolic (E’), and late diastolic/atrial (A’) velocities as well as LV global longitudinal (LVGLS), RV free wall (RVFWS), and global longitudinal LA peak positive strain. Patients were followed every 3 months for the composite outcome of heart failure hospitalization, cardiovascular hospitali

Keywords

MedicineCardiologyInternal medicineEjection fractionHeart failureStrain (injury)Doppler effectDoppler imaging

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