Microscopic Image Analysis of Adenocarcinoma of the Esophagus

TL;DRAbstract

Microscopic Image Analysis (MIA) was applied to quantify nuclear features in adenocarcinoma of the esophagus. It was found that rotation of the axis in the bivariate relation between total optical density (OD) of nuclear DNA and nuclear area corrected the effects of sectioning in this tissue. A stepwise discriminate model was developed which identified high and low survival in patients dependent on MIA measurements of nuclear area, total OD, average OD and texture of nuclear DNA.

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