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Article10.4049/jimmunol.182.supp.39.50

Effects of dietary algal supplementation on bovine immunity (39.50)

Julia M. Green-Johnson,K. A. JOHNSON,Adriana Masotti,Lisa E. Wagar,Sherry Fillmore,Kathleen Glover+3 more-2009-04-01-The Journal of Immunology
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TL;DRAbstract

Abstract Marine algae are primary producers of long chain omega-3 fatty acids and can serve as novel dairy feed supplements with the added potential to influence bovine immunity. Our objective was to assess the immunomodulatory impact of dietary supplementation with different algal types (macroalgae and microalgae). Effects of dietary algal supplementation were examined using a crossover design and a 28 day feeding period with each algal type. Primary immunization with Keyhole Limpet Hemocyanin (KLH) was carried out 8 days into the trial, with secondary immunization 14 days later. KLH-specific serum IgG responses were significantly higher in cows receiving macroalgae-supplemented feed than in cows receiving microalgae-supplemented feed. In contrast, cows receiving microalgae-supplemented feed showed significantly higher levels of macrophage oxidative burst activity in response to PMA challenge in vitro. These results suggest that dietary supplementation with algal products has immunomo

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Abstract Marine algae are primary producers of long chain omega-3 fatty acids and can serve as novel dairy feed supplements with the added potential to influence bovine immunity. Our objective was to assess the immunomodulatory impact of dietary supplementation with different algal types (macroalgae and microalgae). Effects of dietary algal supplementation were examined using a crossover design and a 28 day feeding period with each algal type. Primary immunization with Keyhole Limpet Hemocyanin (KLH) was carried out 8 days into the trial, with secondary immunization 14 days later. KLH-specific serum IgG responses were significantly higher in cows receiving macroalgae-supplemented feed than in cows receiving microalgae-supplemented feed. In contrast, cows receiving microalgae-supplemented feed showed significantly higher levels of macrophage oxidative burst activity in response to PMA challenge in vitro. These results suggest that dietary supplementation with algal products has immunomo

Keywords

BiologyAlgaeImmunityFood scienceKeyhole limpet hemocyaninImmunizationAnimal scienceImmune system

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