Induction of xCT gene expression and L-cystine transport activity by diethyl maleate at the inner blood-retinal barrier.

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Induction of xCT gene expression and L-cystine transport activity by diethyl maleate at the inner blood-retinal barrier.

Masatoshi Tomi,Ken‐ichi Hosoya,Hitomi Takanaga,Sumio Ohtsuki,Tetsuya Terasaki-2002-03-01-PubMed

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TL;DRAbstract

System x(-)(c)-mediated L-cystine uptake appears to be present at the inner BRB. DEM induces L-cystine transport through system x(-)(c) at the inner BRB by enhanced transcription of the xCT gene.

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System x(-)(c)-mediated L-cystine uptake appears to be present at the inner BRB. DEM induces L-cystine transport through system x(-)(c) at the inner BRB by enhanced transcription of the xCT gene.

Keywords

CystineChemistryMolecular biologyIn vitroBiochemistryMessenger RNAGlutamic acidArginine

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