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Mechanistic Studies and Optimization of Microwave-Assisted Palladium-Catalyzed Carbon-Carbon Bond Forming Reactions and an Academic Prospective on “Quality by Design”

Neha K. Grewal-2012-01-01-OpenCommons - UConn (University of Connecticut)

TL;DRAbstract

This compilation of work includes four aspects: (1) an academic review on the significance and implementation of Quality by Design (QbD), (2) mechanistic studies on the palladium-catalyzed synthesis of diarylmethanes, (3) the optimization of microwave-assisted click reactions and Suzuki couplings for use in an undergraduate organic chemistry laboratory manual, and (4) monitoring the progress of organic transformations using Raman spectroscopy.

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This compilation of work includes four aspects: (1) an academic review on the significance and implementation of Quality by Design (QbD), (2) mechanistic studies on the palladium-catalyzed synthesis of diarylmethanes, (3) the optimization of microwave-assisted click reactions and Suzuki couplings for use in an undergraduate organic chemistry laboratory manual, and (4) monitoring the progress of organic transformations using Raman spectroscopy.

Keywords

PalladiumCatalysisCarbon fibersChemistryQuality (philosophy)MicrowaveCarbon–carbon bondOrganic chemistry

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